Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253827 | 0.92 | PPARG (0.41) | ESR2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL7311768 | 0.90 | PPARG (0.46) | PPARGENPP1 | |
| SCHEMBL9254089 | 0.89 | ESR2 (0.39) | ESR2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL9256663 | 0.89 | PPARG (0.43) | PPARG | |
| SCHEMBL9256116 | 0.88 | EGLN1 (0.46) | ESR2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL9253540 | 0.88 | USP2 (0.42) | ESR2PPARGGABRA1GABRG2GABRB3 | |
| Diethylamine SCHEMBL9256272 | 0.87 | PPARG (0.44) | PPARGENPP1 | |
| SCHEMBL9249469 | 0.82 | ENPP1 (0.47) | GABRA1GABRG2GABRB3GABRA2MBOAT4 | |
| SCHEMBL9254113 | 0.80 | PPARG (0.39) | ESR2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL9250470 | 0.79 | SLC33A1 (0.45) | PPARGENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |