Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254956 | 1.00 | HCAR2 (0.49) | HCAR2ACMSDMAPK1KMT2ACYP2A6 | |
| SCHEMBL18985250 | 0.81 | HCAR2 (0.53) | HCAR2MAPK1KMT2AHDAC3TNKS | |
| SCHEMBL18985249 | 0.81 | HCAR2 (0.53) | HCAR2MAPK1KMT2AHDAC3TNKS | |
| SCHEMBL5204967 | 0.77 | HCAR2 (0.45) | HCAR2MAPK1KMT2A | |
| SCHEMBL5204964 | 0.77 | HCAR2 (0.45) | HCAR2MAPK1KMT2A | |
| SCHEMBL5457564 | 0.77 | ESR1 (0.52) | HCAR2ACMSDMAPK1KMT2ACYP2A6 | |
| SCHEMBL6192775 | 0.75 | ERN1 (0.50) | ACMSDCYP2A6CYP2E1CYP2B6ERN1 | |
| SCHEMBL9254826 | 0.75 | NPSR1 (0.51) | HCAR2ACMSDMAPK1KMT2ACYP2A6 | |
| SCHEMBL9254831 | 0.75 | NPSR1 (0.51) | HCAR2ACMSDMAPK1KMT2ACYP2A6 | |
| SCHEMBL27537157 | 0.74 | HCAR2 (0.41) | HCAR2MAPK1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |