Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040268 | 0.80 | TSHR (0.46) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL31540500 | 0.80 | USP2 (0.53) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL17122949 | 0.80 | TSHR (0.46) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL31438712 | 0.80 | USP2 (0.53) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL4012822 | 0.80 | USP2 (0.53) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL15027430 | 0.80 | USP2 (0.53) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL517696 | 0.80 | USP2 (0.53) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL9722899 | 0.80 | TSHR (0.46) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL21056215 | 0.80 | USP2 (0.49) | TSHRUSP2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL10081536 | 0.80 | USP2 (0.53) | TSHRUSP2ALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422004-A | Monocyclic or polycyclic aromatic amide moiety; increased enantioselectivity | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-06-06 | — | — | US | disclosed |
| US-5290440-A | Aromatic amide immobilized on support or forming part of a mobile phase | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| WO-1994000408-A1 | HIGH PERFORMANCE CHIRAL SELECTOR | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-01-06 | — | — | WO | disclosed |