Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 19/20 | 0.88 |
| ▸ | CYSLTR1 | Q9Y271 | 19/20 | 0.88 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122391 | 1.00 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL8122390 | 1.00 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL8123008 | 0.94 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL8123012 | 0.94 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL5200473 | 0.94 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL5200470 | 0.94 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL5200477 | 0.94 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL8127534 | 0.92 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL9250136 | 0.92 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1MEN1RECQLBLM | |
| SCHEMBL8127536 | 0.92 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1MEN1RECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472964-A | Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1995-12-05 | — | — | US | disclosed |