Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255201 | 0.98 | KCNH2 (0.63) | KCNH2CA1CA2CA12CA4 | |
| SCHEMBL5093330 | 0.90 | CHRM2 (0.61) | KCNH2CA1CA2CA12CA4 | |
| SCHEMBL9628053 | 0.89 | KCNH2 (0.73) | KCNH2CA1CA2CA12CA4 | |
| SCHEMBL21404874 | 0.89 | CHRM2 (0.60) | KCNH2CA1CA2CA12CA4 | |
| Hydrochloric Acid SCHEMBL5099421 | 0.89 | CHRM2 (0.59) | KCNH2CA1CA2CA12CA4 | |
| SCHEMBL6575468 | 0.87 | CHRM2 (0.76) | KCNH2CA1CA2CA12CA4 | |
| SCHEMBL30814822 | 0.87 | CHRM2 (0.76) | KCNH2CA1CA2CA12CA4 | |
| Hydrochloric Acid SCHEMBL8895503 | 0.85 | CHRM2 (0.73) | KCNH2CA1CA2CA12CA4 | |
| SCHEMBL1520064 | 0.83 | CHRM2 (0.75) | KCNH2CA1CA2CA12CA4 | |
| SCHEMBL28487383 | 0.83 | MEN1 (0.75) | KCNH2CA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653941-A1 | TARGETED DELIVERY OF GROWTH FACTORS FOR BONE REGENERATION | THE DOW CHEMICAL COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |
| CN-1092076-A | The target release of growth factors for bone regeneration | DOW CHEMICAL CO (US) | 1994-09-14 | — | — | CN | disclosed |
| WO-1994000145-A1 | TARGETED DELIVERY OF GROWTH FACTORS FOR BONE REGENERATION | THE DOW CHEMICAL COMPANY (US) | 1994-01-06 | — | — | WO | disclosed |