Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | DCK | P27707 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24492684 | 0.89 | NPC1 (0.40) | NPC1RAB9ATRPV1CNR2 | |
| SCHEMBL28019896 | 0.82 | GCGR (0.43) | NPC1RAB9ATP53PKMSMN1; SMN2 | |
| SCHEMBL6058880 | 0.81 | HRH3 (0.38) | NPC1RAB9ATP53PKMSMN1; SMN2 | |
| SCHEMBL21448653 | 0.81 | NPC1 (0.38) | NPC1RAB9ATP53PKMSMN1; SMN2 | |
| SCHEMBL294824 | 0.80 | IDO1 (0.42) | DAOCYP17A1CYP21A2CYP11B1TRPV1 | |
| SCHEMBL13632415 | 0.78 | NPC1 (0.44) | NPC1RAB9ATP53PKMSMN1; SMN2 | |
| SCHEMBL31398721 | 0.78 | HSD17B10 (0.40) | NPC1RAB9ATP53PKMSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL6194233 | 0.78 | IDO1 (0.41) | DAOCYP17A1CYP21A2CYP11B1TRPV1 | |
| SCHEMBL13002282 | 0.78 | DAO (0.44) | NPC1RAB9ATP53PKMSMN1; SMN2 | |
| SCHEMBL17108392 | 0.77 | RARB (0.41) | NPC1RAB9ATP53PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454975-A | Electrooptical display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-03 | — | — | US | disclosed |