Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256291 | 1.00 | EPHX2 (0.43) | EPHX2POLBDAOB3GNT2ATM | |
| SCHEMBL9248532 | 0.84 | POLB (0.39) | POLBDAOB3GNT2 | |
| SCHEMBL9248540 | 0.84 | POLB (0.39) | POLBDAOB3GNT2 | |
| SCHEMBL2256797 | 0.79 | DAO (0.47) | POLBDAO | |
| SCHEMBL7551469 | 0.78 | POLB (0.49) | EPHX2POLBDAOB3GNT2ATM | |
| SCHEMBL27349103 | 0.74 | PPARA (0.48) | — | |
| SCHEMBL4563141 | 0.74 | DAO (0.41) | EPHX2DAOB3GNT2 | |
| SCHEMBL5069613 | 0.74 | DAO (0.41) | EPHX2DAOB3GNT2 | |
| SCHEMBL27349061 | 0.74 | MEN1 (0.44) | EPHX2 | |
| SCHEMBL27349107 | 0.74 | MEN1 (0.44) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457180-A | Methods for producing linear thiopeptides using an amino acid ortho amino thioanilide compound | BIOCHEM PHARMA INC. (CA) | 1995-10-10 | — | — | US | disclosed |