Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.61 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25885490 | 0.98 | MEN1 (0.74) | MEN1KMT2APAOXSLC6A5GNAI3 | |
| SCHEMBL25887714 | 0.98 | MEN1 (0.74) | MEN1KMT2APAOXSLC6A5GNAI3 | |
| SCHEMBL15856109 | 0.98 | MEN1 (0.74) | MEN1KMT2APAOXSLC6A5GNAI3 | |
| SCHEMBL7478566 | 0.98 | MEN1 (0.74) | MEN1KMT2APAOXSLC6A5GNAI3 | |
| SCHEMBL14608401 | 0.98 | MEN1 (0.74) | MEN1KMT2APAOXSLC6A5GNAI3 | |
| SCHEMBL15187041 | 0.96 | MEN1 (0.77) | MEN1KMT2APAOXSLC6A5GNAI3 | |
| SCHEMBL7023116 | 0.89 | — | — | |
| SCHEMBL11758762 | 0.87 | MEN1 (0.94) | MEN1KMT2ACASP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9259257 | 0.87 | MEN1 (0.94) | MEN1KMT2ACASP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21765846 | 0.87 | MEN1 (0.94) | MEN1KMT2ACASP2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434213-B1 | Monosubstituted dithiooxamide compounds and their use | MINNESOTA MINING & MFG (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5124308-A | Reacts with transition metal salt for carbonless paper copying | MINNESOTA MINING AND MANUFACTURING COMPANY | 1992-06-23 | — | — | US | disclosed |
| US-5041654-A | Transamination in wallach reaction; controlling temperature; reactant amine concentration | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0431783-A1 | Preparation of monosubstituted dithiooxamide compounds | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |