Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268933 | 0.76 | SLC2A1 (0.47) | MAPTALDH1A1SLC2A1KDM4EHPGD | |
| SCHEMBL12988968 | 0.76 | SLC2A1 (0.47) | MAPTALDH1A1SLC2A1KDM4EHPGD | |
| SCHEMBL15453643 | 0.76 | SLC2A1 (0.47) | MAPTALDH1A1SLC2A1KDM4EHPGD | |
| SCHEMBL9270814 | 0.75 | SLC2A1 (0.46) | MAPTALDH1A1SLC2A1KDM4EHPGD | |
| SCHEMBL9269915 | 0.75 | TYMP (0.51) | MAPTALDH1A1SLC2A1KDM4EHPGD | |
| SCHEMBL8941878 | 0.71 | UPP1 (0.61) | MAPTALDH1A1CYP2C9CYP2C19KDM4E | |
| SCHEMBL8958355 | 0.70 | MAPT (0.50) | MAPTALDH1A1CYP2C9CYP2C19KDM4E | |
| SCHEMBL12990206 | 0.70 | SLC2A1 (0.42) | ALDH1A1SLC2A1TYMPGPR84 | |
| SCHEMBL1539851 | 0.70 | MAPT (0.67) | MAPTALDH1A1CYP2C9CYP2C19KDM4E | |
| SCHEMBL12989506 | 0.70 | SLC2A1 (0.42) | ALDH1A1SLC2A1TYMPGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |