Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247293 | 1.00 | PTAFR (0.56) | PTAFRKDM4EALDH1A1HTR1AHTR2A | |
| SCHEMBL9256730 | 1.00 | PTAFR (0.56) | PTAFRKDM4EALDH1A1HTR1AHTR2A | |
| SCHEMBL9247292 | 1.00 | PTAFR (0.56) | PTAFRKDM4EALDH1A1HTR1AHTR2A | |
| SCHEMBL9256732 | 0.99 | PTAFR (0.56) | PTAFRKDM4EALDH1A1HTR1AHTR2A | |
| SCHEMBL9256729 | 0.99 | PTAFR (0.56) | PTAFRKDM4EALDH1A1HTR1AHTR2A | |
| SCHEMBL9668961 | 0.97 | PTAFR (0.57) | PTAFRKDM4EALDH1A1HTR1AHTR2A | |
| SCHEMBL9257611 | 0.97 | PTAFR (0.57) | PTAFRKDM4EALDH1A1HTR1AHTR2A | |
| SCHEMBL9257616 | 0.97 | PTAFR (0.57) | PTAFRKDM4EALDH1A1HTR1AHTR2A | |
| SCHEMBL9256690 | 0.93 | PTAFR (0.54) | PTAFRKDM4EALDH1A1TBXAS1 | |
| SCHEMBL9256693 | 0.93 | PTAFR (0.54) | PTAFRKDM4EALDH1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |