Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252617 | 0.98 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9252624 | 0.98 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9255998 | 0.98 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9357404 | 0.98 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9843794 | 0.95 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9843797 | 0.95 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9260301 | 0.94 | NPC1 (0.57) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9252422 | 0.94 | NPC1 (0.57) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9252428 | 0.94 | NPC1 (0.57) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9256605 | 0.92 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385693-A | Having rapid response and low phase transition temperature | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0357372-B1 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL CO (JP) | 1994-11-17 | — | — | EP | disclosed |
| US-5264151-A | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-23 | — | — | US | disclosed |