Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257850 | 1.00 | GLA (0.49) | GLATDP1IAPPPTGS1HDAC2 | |
| SCHEMBL9254831 | 0.87 | NPSR1 (0.51) | GLATDP1HDAC2HDAC8CNR1 | |
| SCHEMBL9254826 | 0.87 | NPSR1 (0.51) | GLATDP1HDAC2HDAC8CNR1 | |
| SCHEMBL9454450 | 0.85 | CNR1 (0.45) | HDAC2HDAC8PRMT6CNR1CYP2E1 | |
| SCHEMBL9454454 | 0.85 | CNR1 (0.45) | HDAC2HDAC8PRMT6CNR1CYP2E1 | |
| SCHEMBL23289049 | 0.77 | HDAC2 (0.68) | GLATDP1IAPPPTGS1HDAC2 | |
| SCHEMBL9175193 | 0.77 | ERN1 (0.46) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL9259298 | 0.77 | CCNB2 (0.49) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL9259305 | 0.77 | CCNB2 (0.49) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL9175181 | 0.77 | ERN1 (0.46) | PRMT6CNR1CYP2E1CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |