Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.76 |
| ▸ | CASP2 | P42575 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 5/20 | 0.62 |
| ▸ | NAAA | Q02083 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 2/20 | 0.59 |
| ▸ | CNR2 | P34972 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 4/20 | 0.59 |
| ▸ | PPARD | Q03181 | 4/20 | 0.59 |
| ▸ | PPARA | Q07869 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | TLR2 | O60603 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20844943 | 1.00 | EPHX2 (0.76) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL9827881 | 1.00 | EPHX2 (0.76) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL9829191 | 0.98 | EPHX2 (0.73) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL15259281 | 0.96 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL22684645 | 0.96 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL23052005 | 0.96 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL22072061 | 0.96 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL2150959 | 0.96 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL9266547 | 0.96 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH | |
| SCHEMBL8044633 | 0.96 | EPHX2 (0.81) | EPHX2CASP2KDM4EPLA2G2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | claimed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | claimed |
| US-5391564-A | E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents | SANKYO COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |