Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | ADH1B | P00325 | 2/20 | 0.48 |
| ▸ | ADH1C | P00326 | 2/20 | 0.48 |
| ▸ | ADH1A | P07327 | 2/20 | 0.48 |
| ▸ | ADH4 | P08319 | 2/20 | 0.48 |
| ▸ | ADH7 | P40394 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920547 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL10403846 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL29291467 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL9714408 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL729815 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL29291473 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL2926136 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL28418848 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL10491642 | 1.00 | TSHR (0.70) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL7772441 | 0.98 | TSHR (0.67) | TSHRSMN1; SMN2ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| CN-111481469-B | copolymer | 宝丽化学工业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-111358713-B | copolymer | 宝丽化学工业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-4215188-A1 | AN AMINO LIPID, PREPARATION METHOD AND APPLICATION THEREOF | Shenzhen MagicRNA Biotechnology Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
| CN-111329788-B | Copolymer | 宝丽化学工业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-111329787-B | Copolymer | 宝丽化学工业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-111481469-A | Copolymer | 宝丽化学工业有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111358713-A | Copolymer | 宝丽化学工业有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-111329788-A | Copolymer | 宝丽化学工业有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-111329787-A | Copolymer | 宝丽化学工业有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-1028427-C | Rhizoxin derivatives and their use as antitumor agents | SANKYO CO (JP) | 1995-05-17 | — | — | CN | disclosed |
| US-5391564-A | E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents | SANKYO COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| CN-1040982-A | Nitragin (rhizoxin) derivative and as antineoplastic agent | SANKYO CO (JP) | 1990-04-04 | — | — | CN | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |