Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.81 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.81 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.71 |
| ▸ | ABCC2 | Q92887 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.71 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.71 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278598 | 0.93 | CYSLTR1 (0.78) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9278602 | 0.93 | CYSLTR1 (0.78) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9267947 | 0.90 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9265732 | 0.90 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9120135 | 0.88 | CYSLTR1 (0.89) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9260040 | 0.86 | CYSLTR1 (0.91) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9260038 | 0.86 | CYSLTR1 (0.91) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| Dimethylcarbate SCHEMBL9327878 | 0.85 | CYSLTR1 (0.90) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9262890 | 0.84 | CYSLTR1 (0.88) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9268119 | 0.84 | CYSLTR1 (0.70) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428171-A | Leukotrienes antagonist; antiasthmatic, antiallergic, anti-inflammatory and cytoprotective agent | MERCK FROSST CANADA, INC. (CA) | 1995-06-27 | — | — | US | disclosed |
| EP-0233763-A2 | 2-Substituted quinoline dioic acids | MERCK FROSST CANADA INC. (CA) | 1987-08-26 | — | — | EP | disclosed |