Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 19/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405064 | 0.88 | HAVCR2 (0.67) | HAVCR2HSD17B10XDH | |
| SCHEMBL404677 | 0.88 | HAVCR2 (0.60) | HAVCR2HSD17B10XDH | |
| SCHEMBL405861 | 0.88 | HAVCR2 (0.60) | HAVCR2HSD17B10XDH | |
| SCHEMBL404891 | 0.88 | HAVCR2 (0.70) | HAVCR2HSD17B10 | |
| SCHEMBL405538 | 0.85 | HAVCR2 (0.63) | HAVCR2HSD17B10XDH | |
| SCHEMBL404463 | 0.85 | HAVCR2 (0.71) | HAVCR2HSD17B10 | |
| SCHEMBL11177065 | 0.82 | HSD17B10 (0.66) | HAVCR2HSD17B10XDH | |
| SCHEMBL404765 | 0.82 | HAVCR2 (0.75) | HAVCR2HSD17B10XDH | |
| SCHEMBL404656 | 0.82 | HAVCR2 (0.75) | HAVCR2HSD17B10XDH | |
| SCHEMBL8861987 | 0.81 | HAVCR2 (0.46) | HAVCR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673249-A1 | TRIAZOLOQUINAZOLINES FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF Aktiengesellschaft (DE) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013294-A1 | TRIAZOLOQUINAZOLINES FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 1994-06-23 | — | — | WO | disclosed |