Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL19716 | 1.00 | — | — | |
| Bromide SCHEMBL27797674 | 1.00 | — | — | |
| Bromide SCHEMBL2195416 | 1.00 | — | — | |
| Bromide SCHEMBL14690681 | 1.00 | — | — | |
| Bromide SCHEMBL25327329 | 0.82 | — | — | |
| Bromide SCHEMBL8587438 | 0.82 | — | — | |
| Bromide SCHEMBL4453349 | 0.82 | — | — | |
| Bromide SCHEMBL8409590 | 0.82 | — | — | |
| Bromide SCHEMBL14958466 | 0.82 | — | — | |
| Bromide SCHEMBL18066260 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391767-A | Catalytic reaction of alkylene oxide with carbon dioxide in presence of mixed catalyst which can be regenerated by treating with halogen compound | BAYER AKTIENGESELLSCHAFT (DE) | 1995-02-21 | — | — | US | disclosed |