Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12677249 | 0.82 | EPHX1 (0.76) | EPHX1TP53HPGDALOX12ALDH1A1 | |
| SCHEMBL2352072 | 0.76 | EPHX1 (0.61) | EPHX1TP53HPGDALOX12ALDH1A1 | |
| SCHEMBL4915364 | 0.76 | EPHX1 (0.61) | EPHX1TP53HPGDALOX12ALDH1A1 | |
| SCHEMBL9847359 | 0.73 | KDM5A (0.43) | LMNAUSP2 | |
| SCHEMBL17393581 | 0.73 | — | — | |
| SCHEMBL25304106 | 0.71 | EPHX1 (1.00) | EPHX1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL2731115 | 0.71 | EPHX1 (1.00) | EPHX1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL11122975 | 0.71 | EPHX1 (1.00) | EPHX1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL25262887 | 0.71 | EPHX1 (1.00) | EPHX1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL250637 | 0.71 | EPHX1 (0.61) | EPHX1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455355-A | Postemergence, preemergence herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-03 | — | — | US | disclosed |
| US-5298632-A | Herbicidal pyrimidine compounds, compositions containing the same and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5232897-A | Herbicidal pyrimidine compounds, compositions containing the same and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0457505-A2 | Pyrimidine derivatives and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-21 | — | — | EP | disclosed |