Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263799 | 0.81 | SLC2A1 (0.59) | KDM4ESLC2A1ALDH1A1MAPTMEN1 | |
| SCHEMBL9267776 | 0.80 | SLC2A1 (0.57) | KDM4ESLC2A1ALDH1A1MAPTMEN1 | |
| SCHEMBL9272741 | 0.77 | MEN1 (0.45) | KDM4ESLC2A1ALDH1A1MAPTMEN1 | |
| SCHEMBL9269675 | 0.75 | KDM4E (0.50) | KDM4EHSD11B1ALDH1A1MAPTMEN1 | |
| SCHEMBL4487870 | 0.74 | SLC2A1 (0.40) | KDM4ESLC2A1ALDH1A1MAPTMEN1 | |
| SCHEMBL9261054 | 0.74 | SLC2A1 (0.74) | SLC2A1ALDH1A1MAPTMEN1POLB | |
| SCHEMBL9270873 | 0.74 | SLC2A1 (0.51) | KDM4ESLC2A1ALDH1A1MAPTMEN1 | |
| SCHEMBL9271041 | 0.72 | SLC2A1 (0.50) | SLC2A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL9267712 | 0.72 | SLC2A1 (0.50) | KDM4ESLC2A1ALDH1A1MEN1POLB | |
| SCHEMBL9268614 | 0.72 | SLC2A1 (0.56) | SLC2A1MAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |