Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BCKDK | O14874 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261936 | 0.88 | MCL1 (0.51) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL7728937 | 0.81 | MCL1 (0.67) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL15619574 | 0.80 | MCL1 (0.71) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL417349 | 0.78 | MCL1 (1.00) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL4277521 | 0.78 | MCL1 (0.67) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL11398642 | 0.77 | MCL1 (0.61) | MCL1BCL2L1RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL11398368 | 0.76 | MCL1 (0.97) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL11398641 | 0.75 | MCL1 (0.58) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL31564735 | 0.74 | STING1 (0.50) | MCL1BCL2L1LMNABCKDKGPR35 | |
| SCHEMBL2610280 | 0.74 | MCL1 (0.61) | MCL1BCL2L1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428043-A | Tricyclic-cyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1995-06-27 | — | — | US | disclosed |