Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 15/20 | 0.60 |
| ▸ | ESR1 | P03372 | 10/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766383 | 0.78 | KDM4E (0.74) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL15413701 | 0.78 | ESR2 (0.62) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL15413700 | 0.77 | ESR2 (0.57) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6825266 | 0.76 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6828759 | 0.73 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL22413393 | 0.73 | ESR2 (0.71) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL31060326 | 0.73 | KDM4E (0.70) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL2555897 | 0.73 | KDM4E (0.70) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL7824164 | 0.72 | KDM4E (0.66) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL9211529 | 0.72 | KDM4E (0.66) | ESR2ESR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0547145-A1 | ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS | SCHERING CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |