SCHEMBL9260232

SCHEMBL9260232

CCCOCCCOCCc1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
ESR1 P03372 4/20 0.53
SLC6A2 P23975 4/20 0.53
ADRA2A P08913 3/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
KDM4E B2RXH2 2/20 0.53
CHRM1 P11229 2/20 0.53
LMNA P02545 2/20 0.53
CYP3A4 P08684 2/20 0.53
SHBG P04278 1/20 0.53
TP53 P04637 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53
HSPE1 P61604 1/20 0.53
HIF1A Q16665 1/20 0.53
TST Q16762 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8914902 0.94 ESR1 (0.53) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL9260721 0.91 ESR1 (0.61) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL11237561 0.91 ESR1 (0.60) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL8939444 0.91 ESR1 (0.60) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL28656684 0.89 ESR1 (0.63) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL9253926 0.89 ESR1 (0.63) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL25299458 0.87 ESR1 (0.67) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL31651135 0.87 ESR1 (0.67) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL11228902 0.87 ESR1 (0.67) ALDH1A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL31651133 0.87 ESR1 (0.67) ALDH1A1ESR1SLC6A2ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5385693-A Having rapid response and low phase transition temperature SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-31 US disclosed
EP-0357372-B1 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL CO (JP) 1994-11-17 EP disclosed
US-5264151-A Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
US-5124070-A High speed response SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-23 US disclosed