Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.58 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.57 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.56 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.56 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.54 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.54 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481521 | 1.00 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL482186 | 1.00 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL8616133 | 1.00 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL9260385 | 1.00 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL8342199 | 1.00 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL8983412 | 1.00 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| Hydrochloric Acid SCHEMBL9851469 | 0.99 | KDM4E (0.58) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL9315796 | 0.85 | KDM4E (0.47) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL9395036 | 0.85 | KDM4E (0.44) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL9394349 | 0.85 | KDM4E (0.44) | KDM4EABCB1ABCC9KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466817-A | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5276168-A | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E. R. SQUIBB & SONS, INC. (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0462761-A2 | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents | E.R. SQUIBB & SONS, INC. (US) | 1991-12-27 | — | — | EP | disclosed |
| EP-0139992-B1 | CHROMANOL DERIVATIVES | BEECHAM GROUP PLC (GB) | 1988-12-28 | — | — | EP | disclosed |
| US-4687779-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-08-18 | — | — | US | disclosed |