Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ACP3 | P15309 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915620 | 0.98 | MAPK1 (0.57) | MAPK1ACP3KMT2ADPP4FOLH1 | |
| SCHEMBL9260425 | 0.96 | MAPK1 (0.56) | MAPK1ACP3KMT2ADPP4FOLH1 | |
| SCHEMBL11406555 | 0.84 | ACP3 (0.50) | MAPK1ACP3KMT2ADPP4FOLH1 | |
| SCHEMBL9179278 | 0.81 | KMT2A (0.47) | MAPK1KMT2ADPP4FOLH1PDCD1 | |
| SCHEMBL27463949 | 0.79 | KMT2A (0.49) | MAPK1KMT2ADPP4FOLH1PDCD1 | |
| SCHEMBL8053801 | 0.79 | ACP3 (0.65) | ACP3KMT2AMMP2MMP9MMP12 | |
| SCHEMBL29707862 | 0.79 | ACP3 (0.65) | ACP3KMT2AMMP2MMP9MMP12 | |
| Phosphoric Acid SCHEMBL28234427 | 0.78 | KMT2A (0.52) | MAPK1KMT2ADPP4FOLH1PDCD1 | |
| SCHEMBL916335 | 0.78 | KMT2A (0.44) | MAPK1KMT2ADPP4FOLH1PDCD1 | |
| Phosphoric Acid SCHEMBL28852127 | 0.77 | PDCD1 (0.52) | ACP3KMT2ADPP4FOLH1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661978-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1995-07-12 | — | — | EP | claimed |
| WO-1994007501-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1994-04-14 | — | — | WO | claimed |