Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30422264 | 1.00 | IDO1 (0.53) | IDO1ALDH1A1TSHRHTTXBP1 | |
| Hydrochloric Acid SCHEMBL28558644 | 0.98 | IDO1 (0.55) | IDO1ALDH1A1TSHRHTTXBP1 | |
| Methane SCHEMBL28634069 | 0.98 | IDO1 (0.52) | IDO1ALDH1A1TSHRHTTXBP1 | |
| SCHEMBL4970281 | 0.94 | TSHR (0.48) | IDO1ALDH1A1TSHRHTTXBP1 | |
| SCHEMBL30094172 | 0.86 | IDO1 (0.50) | IDO1HTR6 | |
| SCHEMBL1117278 | 0.86 | IDO1 (0.50) | IDO1HTR6 | |
| SCHEMBL29156852 | 0.85 | IDO1 (0.41) | IDO1ALDH1A1TSHRHTTXBP1 | |
| SCHEMBL440138 | 0.79 | HTR2A (0.54) | IDO1 | |
| SCHEMBL29793145 | 0.79 | HTR2A (0.54) | IDO1 | |
| SCHEMBL145977 | 0.77 | IDO1 (0.57) | IDO1TSHRHTTADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203921-B | Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-30 | — | — | CN | claimed |
| CN-118043311-A | Chlorinated tetralin compounds and pharmaceutical compositions | 斯普林渥克斯治疗有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-118043311-A | Chlorinated tetralin compounds and pharmaceutical compositions | 斯普林渥克斯治疗有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116194456-A | Preparation of heterocyclic compounds as KRAS inhibitors and methods of use thereof | 上海科州药物研发有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115666513-A | Novel pharmaceutical compositions for drug delivery | 奥瑞克索股份公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115397264-A | Formula for preventing or reducing clostridium difficile infection | 孢子原有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115135331-A | Rhodospirillum rubrum cells for lowering plasma cholesterol while leaving other serum protein levels unaffected | 埃兹科尔公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-114867363-A | Granules comprising a lipid matrix core and an active ingredient | 比利时胶囊公司 | 2022-08-05 | — | — | CN | disclosed |
| WO-2021219072-A1 | PREPARATION AND APPLICATION METHOD OF HETEROCYCLIC COMPOUND AS KRAS INHIBITOR | 上海科州药物研发有限公司 (CN) | 2021-11-04 | — | — | WO | disclosed |
| CN-110248815-B | Method for producing laminated printed matter, and laminated printed matter | 富士胶片株式会社 | 2021-09-10 | — | — | CN | disclosed |
| EP-0707570-B1 | ISOQUINOLINE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1998-05-06 | — | — | EP | disclosed |
| EP-0707570-A1 | ISOQUINOLINE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0649419-A1 | N-CYCLOALKYLPIPERAZINE DERIVATIVES, METHODS OF OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES MERAM (FR) | 1995-04-26 | — | — | EP | disclosed |
| WO-1995000489-A1 | ISOQUINOLINE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |
| US-5369214-A | Method for selective dehalogenation of halogenated polyaromatic compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1994-11-29 | — | — | US | disclosed |
| WO-1994002473-A1 | N-CYCLOALKYLPIPERAZINE DERIVATIVES, METHODS OF OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES MERAM (FR) | 1994-02-03 | — | — | WO | disclosed |
| EP-0165780-B1 | IMIDAZOLYL, TRIAZOLYL, AND TETRAZOLYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4659730-A | PREVENTION OF ESTROGEN-DEPENDENT DISEASES | ELI LILLY AND COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0165780-A1 | Imidazolyl, triazolyl, and tetrazolyl compounds | ELI LILLY AND COMPANY (US) | 1985-12-27 | — | — | EP | disclosed |
| US-4533777-A | HALOALKYLATION OF A BENZENE RING USING CARBON TETRACHLORIDE AND HYDROFLUORIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-06 | — | — | US | disclosed |