Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 9/20 | 0.60 |
| ▸ | PPARA | Q07869 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29691546 | 0.84 | FFAR1 (0.70) | FFAR1PPARGPPARAMAPT | |
| SCHEMBL3278854 | 0.82 | MAPT (0.68) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL13721818 | 0.81 | FFAR1 (0.63) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL4850515 | 0.81 | FFAR1 (0.71) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL6156630 | 0.81 | FFAR1 (0.71) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL4030957 | 0.80 | FFAR1 (0.70) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL14281854 | 0.80 | PPARG (0.57) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL14307032 | 0.80 | PPARG (0.59) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL14281856 | 0.80 | PPARG (0.61) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL14302921 | 0.80 | PPARG (0.61) | FFAR1PPARGPPARAMAPTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459154-A | Enzyme inhibitors as antiinflammatory agents and treatment of atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |