Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 9/20 | 0.59 |
| ▸ | CNR1 | P21554 | 7/20 | 0.59 |
| ▸ | DAGLB | Q8NCG7 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.54 |
| ▸ | LPL | P06858 | 1/20 | 0.54 |
| ▸ | LIPC | P11150 | 1/20 | 0.54 |
| ▸ | PNLIP | P16233 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | FASN | P49327 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.54 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269035 | 1.00 | DAGLA (0.59) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL9265104 | 1.00 | DAGLA (0.59) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL9031936 | 0.93 | DAGLA (0.69) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL9033377 | 0.93 | DAGLA (0.69) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL9034220 | 0.93 | DAGLA (0.63) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL9271032 | 0.89 | DAGLA (0.55) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL9032293 | 0.88 | DAGLA (0.52) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL9254870 | 0.86 | DAGLA (0.56) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL9259331 | 0.85 | DAGLA (0.59) | DAGLACNR1DAGLBMAPTMEN1 | |
| SCHEMBL7629527 | 0.82 | DAGLA (0.70) | DAGLACNR1DAGLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466708-A | Carbamyloxyoxetanone compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5376674-A | Lipase inhibitors | HOFFMAN-LA ROCHE INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5260310-A | Oxetanone compounds and pharmaceutical compositions containing them | HOFFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |