SCHEMBL92630

SCHEMBL92630

COCCN1CCNCC1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SIGMAR1 Q99720 3/20 0.44
CXCR4 P61073 2/20 0.43
LTA4H P09960 1/20 0.41
HSD17B10 Q99714 1/20 0.39
GBA1 P04062 1/20 0.39
HSD11B1 P28845 1/20 0.38
RAD52 P43351 1/20 0.37
HRH2 P25021 1/20 0.37
HRH1 P35367 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1476930 1.00 MEN1 (0.54) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
Hydrochloric Acid SCHEMBL2916344 0.98 MEN1 (0.53) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
Hydrochloric Acid SCHEMBL7316900 0.98 MEN1 (0.53) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
Piperazine SCHEMBL28220981 0.98 MEN1 (0.53) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
Cyclohexane SCHEMBL2487255 0.96 MEN1 (0.51) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
SCHEMBL2189051 0.92 CXCR4 (0.57) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
Hydrochloric Acid SCHEMBL28701161 0.90 CXCR4 (0.55) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
SCHEMBL16758734 0.87 MEN1 (0.49) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
SCHEMBL20745043 0.87 MEN1 (0.49) MEN1KMT2APOLBSMN1; SMN2SIGMAR1
SCHEMBL31694361 0.87 MEN1 (0.49) MEN1KMT2APOLBSMN1; SMN2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2545 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546089-A Tetrahydroisoquinoline derivative and application thereof as acrB efflux pump inhibitor with membrane permeabilization function in antibiosis 山东大学 2024-08-27 CN claimed
CN-118239923-A Compounds useful as inhibitors of factor XIIa, pharmaceutical compositions and uses thereof 合肥工业大学 2024-06-25 CN claimed
CN-116764689-A Method for stripping carbamate from ion exchange resin 埃克-泰克股份有限公司 2023-09-19 CN claimed
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-07-06 US claimed
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP claimed
CN-115916776-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2023-04-04 CN claimed
CN-115710251-A Myeloid differentiation factor 88 inhibitor and preparation method and application thereof 杭州医学院 2023-02-24 CN claimed
CN-114740694-A Photoresist stripping liquid and preparation method thereof 芯越微电子材料(嘉兴)有限公司 2022-07-12 CN claimed
CN-110452130-B Obovatol Mannich base derivative and preparation method and application thereof 山西农业大学 2022-03-01 CN claimed
WO-2021252555-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-16 WO claimed
EP-0927173-B1 SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL UCB SA (BE) 2002-06-12 EP claimed
US-6255487-B1 PREPARING 2-(2-(4-((4-CHLOROPHENYL)PHENYLMETHYL)-1-PIPER-AZINYL)ETHOXY)ACETIC ACID VIA REACTING SUBSTITUTED (2-((1-PIPERAZINYL)ETHOXY)METHYL COMPOUND WITH A DIPHENYLMETHYL HALIDE, THEN HYDROLYZING IN ALCOHOLIC MEDIUM WITH ACID/BASE UCB, S.A. (BE) 2001-07-03 US claimed
US-6140501-A CHEMICAL INTERMEDIATES UCB, S.A. (BE) 2000-10-31 US claimed
EP-0927173-A1 SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL UCB, S.A. (BE) 1999-07-07 EP claimed
WO-1997037982-A1 NOVEL SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL UCB S.A. (BE) 1997-10-16 WO claimed
CN-1025999-C Imidazo [4,5-B] quinolinyloxyalkanoic acid amides with enhanced water solubility BRISTOL MYERS SQUIBB CO (US) 1994-09-28 CN claimed
CN-1051359-A Improved imidazo [4, the 5-b] quinolinyloxyalkanoic acid amides of water-soluble degree BRISTOL MYERS SQUIBB CO (US) 1991-05-15 CN claimed
CN-1003236-B Preparation method of 6, 7-disubstituted-1-cyclopropyl-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid 拜尔公司 1989-02-08 CN claimed
US-4046772-A MUSCLE RELAXANTS, ANTICONVULSANTS, SEDATIVES, TRANQUILIZERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-09-06 US claimed
US-4017620-A MUSCLE RELAXANTS, ANTICONVULSANTS, SEDATIVES, TRANQUILIZERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-04-12 US claimed