Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 3/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263161 | 1.00 | NPC1 (0.42) | NPC1RAB9AMAPTGAAGFER | |
| SCHEMBL9272688 | 0.88 | GFER (0.40) | NPC1RAB9AMAPTGAAGFER | |
| SCHEMBL9272683 | 0.88 | GFER (0.40) | NPC1RAB9AMAPTGAAGFER | |
| SCHEMBL9272677 | 0.88 | GFER (0.40) | NPC1RAB9AMAPTGAAGFER | |
| SCHEMBL8554123 | 0.84 | MAPT (0.41) | MAPTGAAMEN1KMT2A | |
| SCHEMBL8554126 | 0.84 | MAPT (0.41) | MAPTGAAMEN1KMT2A | |
| SCHEMBL9270753 | 0.82 | APP (0.49) | NPC1RAB9AMAPTGAASMN1; SMN2 | |
| SCHEMBL9270748 | 0.82 | APP (0.49) | NPC1RAB9AMAPTGAASMN1; SMN2 | |
| SCHEMBL9269933 | 0.81 | PDE4B (0.42) | NPC1RAB9AMAPTGFERAXL | |
| SCHEMBL9269941 | 0.81 | PDE4B (0.42) | NPC1RAB9AMAPTGFERAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011890-A1 | 6-FLUOROBENZOTHIAZOLES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1995-05-04 | — | — | WO | disclosed |