Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | F13A1 | P00488 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 4/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331570 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA | |
| SCHEMBL11472210 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA | |
| SCHEMBL9661496 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA | |
| SCHEMBL1916566 | 0.86 | KMT2A (0.54) | SMN1; SMN2KDM4EF13A1ALDH1A1MAPT | |
| SCHEMBL22922181 | 0.85 | CYP4F2 (0.59) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL10592850 | 0.85 | KDM4E (0.84) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA | |
| SCHEMBL9331035 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA | |
| SCHEMBL11473795 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA | |
| SCHEMBL11133179 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA | |
| SCHEMBL11471927 | 0.82 | KDM4E (0.68) | SMN1; SMN2KDM4EF13A1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |