SCHEMBL926510

SCHEMBL926510

CCO[Si](CCc1cccc(C(C)Cl)c1)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31
NOS1 P29475 2/20 0.30
NOS2 P35228 2/20 0.30
MRGPRX4 Q96LA9 1/20 0.30
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL928561 0.87 CYP4F2 (0.31) CYP4F2CYP4A11PGK1PGK2IDO1
SCHEMBL926365 0.86 CYP2D6 (0.34)
SCHEMBL926552 0.85 CYP4F2 (0.34) CYP4F2CYP4A11NOS1NOS2MRGPRX4
SCHEMBL2891094 0.85 CYP4F2 (0.31) CYP4F2CYP4A11NOS1NOS2MRGPRX4
SCHEMBL927532 0.85 TAAR1 (0.36) CYP4F2CYP4A11PGK1PGK2IDO1
SCHEMBL574686 0.82 CYP4F2 (0.38) CYP4F2CYP4A11NOS1NOS2
SCHEMBL929187 0.81 TSHR (0.34) IDO1
SCHEMBL2883841 0.81 CYP4F2 (0.31) CYP4F2CYP4A11
SCHEMBL2887344 0.81 CYP4F2 (0.31) CYP4F2CYP4A11
SCHEMBL926947 0.78 TSHR (0.34) CYP4F2CYP4A11NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121349-B1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2010-11-17 EP claimed
EP-2207782-A2 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM Momentive Performance Materials Inc. (US) 2010-07-21 EP claimed
US-7625965-B2 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-12-01 US claimed
EP-2121349-A1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2009-11-25 EP claimed
WO-2009058373-A2 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-07 WO claimed
US-20090111923-A1 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2009-04-30 US claimed
WO-2008097587-A1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC (US) 2008-08-14 WO claimed
US-20080194746-A1 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2008-08-14 US claimed
EP-2708546-B1 Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MAT INC (US) 2016-01-06 EP disclosed
CN-101910185-B Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MAT INC 2014-04-30 CN disclosed
EP-2708546-A1 Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom Momentive Performance Materials Inc. (US) 2014-03-19 EP disclosed
EP-2207782-B1 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2014-02-26 EP disclosed
US-8372906-B2 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-02-12 US disclosed
US-20110003922-A1 Halo-Functional Silane, Process For Its Preparation, Rubber Composition Containing Same and Articles Manufactured Therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-06 US disclosed
US-7816435-B2 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-10-19 US disclosed
US-7625965-B2 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-12-01 US disclosed
EP-2121349-A1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2009-11-25 EP disclosed
US-20090111923-A1 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2009-04-30 US disclosed
WO-2008097587-A1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC (US) 2008-08-14 WO disclosed
US-20080194746-A1 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2008-08-14 US disclosed