Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265207 | 1.00 | ALB (0.68) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9265648 | 1.00 | ALB (0.68) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9265625 | 1.00 | ALB (0.68) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9262981 | 1.00 | ALB (0.68) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9262988 | 1.00 | ALB (0.68) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9260599 | 0.99 | ALB (0.69) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9260588 | 0.99 | ALB (0.69) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9094074 | 0.97 | ALB (0.69) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9094063 | 0.97 | ALB (0.69) | ALBCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL9264856 | 0.97 | ALB (0.68) | ALBCYP3A4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577003-A1 | Thiazolylvinylphenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-05 | — | — | EP | claimed |
| US-5399702-A | Leukotriene antagonists; antiasthmatic, antiallergen, and antianaphylactic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0577003-A1 | Thiazolylvinylphenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-05 | — | — | EP | disclosed |
| US-5273986-A | A substituted phenylalkyleneamidophenyleneethylene thiazole | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |