Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178576 | 0.85 | HRH1 (0.73) | HRH1MEN1LMNAADRB2CHRM2 | |
| SCHEMBL2738853 | 0.84 | HRH1 (0.68) | HRH1MEN1LMNAADRB2CHRM2 | |
| SCHEMBL6177391 | 0.83 | HRH1 (0.67) | HRH1MEN1LMNAADRB2CHRM2 | |
| SCHEMBL8878164 | 0.83 | FNTA (0.71) | HRH1FNTAFNTBSLC6A15 | |
| SCHEMBL6177566 | 0.81 | HRH1 (0.67) | HRH1MEN1LMNAADRB2CHRM2 | |
| SCHEMBL6177784 | 0.80 | HRH1 (0.63) | HRH1MEN1LMNAADRB2CHRM2 | |
| SCHEMBL6179128 | 0.80 | HRH1 (0.63) | HRH1MEN1LMNAADRB2CHRM2 | |
| Desloratadine SCHEMBL4425 | 0.76 | HRH1 (1.00) | HRH1MEN1LMNAADRB2CHRM2 | |
| Desloratadine SCHEMBL29390260 | 0.76 | HRH1 (1.00) | HRH1MEN1LMNAADRB2CHRM2 | |
| Desloratadine SCHEMBL29371361 | 0.76 | HRH1 (1.00) | HRH1MEN1LMNAADRB2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422351-A | Antiallergens; antiinflammatory agents | SCHERING CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |