Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 7/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265474 | 0.99 | MAPT (0.56) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9271331 | 0.91 | MAPT (0.49) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9261441 | 0.89 | MAPT (0.53) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9270924 | 0.88 | KMT2A (0.52) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9272600 | 0.88 | MAPT (0.55) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9272965 | 0.88 | MAPT (0.52) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9269704 | 0.88 | MAPT (0.52) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9273576 | 0.87 | KMT2A (0.54) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9266390 | 0.87 | MAPT (0.54) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL9270741 | 0.87 | KMT2A (0.54) | MAPTSMN1; SMN2RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393458-A | Aromatic esters and liquid crystal mixtures containing same | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| US-5326498-A | Electrooptics, ferroelectricity | HOFFMANN-LA ROCHE INC. (US) | 1994-07-05 | — | — | US | disclosed |