Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17565792 | 0.85 | FFAR3 (0.39) | FFAR3CES2CES1TDP1ALDH1A1 | |
| SCHEMBL7103464 | 0.81 | TSHR (0.38) | FFAR3EP300TSHR | |
| SCHEMBL7103467 | 0.81 | TSHR (0.38) | FFAR3EP300TSHR | |
| SCHEMBL17610271 | 0.75 | FFAR3 (0.33) | FFAR3EP300CES2CES1 | |
| SCHEMBL3355710 | 0.75 | FFAR3 (0.33) | FFAR3EP300CES2CES1 | |
| SCHEMBL166922 | 0.75 | FFAR3 (0.33) | FFAR3EP300CES2CES1 | |
| SCHEMBL9267326 | 0.75 | FFAR3 (0.33) | FFAR3EP300CES2CES1 | |
| SCHEMBL216025 | 0.75 | — | — | |
| SCHEMBL5697356 | 0.74 | EP300 (0.32) | FFAR3EP300 | |
| SCHEMBL30444526 | 0.74 | EP300 (0.32) | FFAR3EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432182-A | Inhibitors of gastric acid secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-07-11 | — | — | US | disclosed |
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |