Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3183005 | 0.88 | MEN1 (0.52) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL27799588 | 0.86 | MEN1 (0.50) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL20399800 | 0.83 | NPC1 (0.53) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL20547225 | 0.83 | MEN1 (0.52) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL20410742 | 0.83 | NPC1 (0.48) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL30360502 | 0.83 | NPC1 (0.48) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL9268473 | 0.82 | MEN1 (0.49) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL30069356 | 0.82 | MEN1 (0.46) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL15504877 | 0.80 | MEN1 (0.57) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL2673587 | 0.79 | KMT2A (0.56) | MEN1KMT2ANPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387688-A | Intermediates for making analgesic N-phenyl-N-(3-OR1 -3-Me-4-piperidinyl)amides | GLAXO INC. (US) | 1995-02-07 | — | — | US | disclosed |
| US-5214148-A | Analgesic N-phenyl-N-(3-OR1 -3-ME-4-piperidinyl)amides | GLAXO INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5130321-A | Analgesic n-phenyl-n-(3-or 1-3-me-4-piperidinyl)amides | GLAXO INC. (US) | 1992-07-14 | — | — | US | disclosed |