Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268968 | 0.99 | RARB (0.48) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9270491 | 0.96 | MAPT (0.46) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9270924 | 0.95 | KMT2A (0.52) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9270025 | 0.94 | KMT2A (0.54) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL10427620 | 0.94 | KMT2A (0.54) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9273576 | 0.94 | KMT2A (0.54) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9270073 | 0.94 | KMT2A (0.54) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9270741 | 0.94 | KMT2A (0.54) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL7646144 | 0.94 | KMT2A (0.54) | RARBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9269704 | 0.93 | MAPT (0.52) | RARBMAPTSMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393458-A | Aromatic esters and liquid crystal mixtures containing same | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| US-5326498-A | Electrooptics, ferroelectricity | HOFFMANN-LA ROCHE INC. (US) | 1994-07-05 | — | — | US | disclosed |