Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973409 | 0.87 | BTK (0.46) | BTKNFKB1NFKB2RELACTSK | |
| SCHEMBL3431751 | 0.86 | BTK (0.45) | BTKNFKB1NFKB2RELACTSK | |
| SCHEMBL5044643 | 0.86 | BTK (0.45) | BTKNFKB1NFKB2RELACTSK | |
| SCHEMBL1380088 | 0.76 | BTK (0.53) | BTKNFKB1NFKB2RELACTSK | |
| SCHEMBL3702157 | 0.75 | BTK (0.61) | BTKNFKB1NFKB2RELACTSK | |
| SCHEMBL3702152 | 0.75 | BTK (0.61) | BTKNFKB1NFKB2RELACTSK | |
| SCHEMBL10343938 | 0.75 | BTK (0.61) | BTKNFKB1NFKB2RELACTSK | |
| SCHEMBL1406894 | 0.75 | BTK (0.61) | BTKNFKB1NFKB2RELACTSK | |
| Methyl Alcohol SCHEMBL28082230 | 0.74 | BTK (0.59) | BTKNFKB1NFKB2RELACTSK | |
| SCHEMBL1385999 | 0.73 | BTK (0.50) | BTKNFKB1NFKB2RELACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407932-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0393400-B1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KK (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5245037-A | Synthetic bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0393400-A1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-24 | — | — | EP | disclosed |