Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273093 | 0.91 | AVPR1A (0.57) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9269394 | 0.87 | PTGER1 (0.61) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9269901 | 0.85 | MEN1 (0.52) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9277277 | 0.84 | PTGER1 (0.60) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9275447 | 0.84 | MAPT (0.59) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9269912 | 0.83 | MEN1 (0.51) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9273084 | 0.82 | PTGER1 (0.55) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9272921 | 0.82 | PTGER1 (0.57) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9278010 | 0.81 | MEN1 (0.53) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9049054 | 0.80 | PTGER1 (0.55) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461047-A | Analgesics and treats prostaglandin-E2 mediated diseases in animals | G. D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | disclosed |
| US-5354747-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | disclosed |