SCHEMBL9272467

SCHEMBL9272467

CC(C)CC1NC(=O)OC1c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 9/20 0.41
CYP2D6 P10635 1/20 0.40
CA2 P00918 1/20 0.38
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
PAX8 Q06710 1/20 0.37
LMNA P02545 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
ALDH1A1 P00352 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9798245 1.00 GRM5 (0.41) GRM5CYP2D6CA2GAAHTT
SCHEMBL9449383 0.84 GRM5 (0.40) GRM5CYP2D6CA2LMNAADORA3
SCHEMBL15699098 0.81 GRM5 (0.44) GRM5CYP2D6CA2LMNAADORA3
SCHEMBL15676299 0.81 GRM5 (0.44) GRM5CYP2D6CA2LMNAADORA3
SCHEMBL19061962 0.81 GRM5 (0.44) GRM5CYP2D6CA2LMNAADORA3
SCHEMBL19795866 0.81 GRM5 (0.44) GRM5CYP2D6CA2LMNAADORA3
SCHEMBL15676298 0.81 GRM5 (0.44) GRM5CYP2D6CA2LMNAADORA3
SCHEMBL15676054 0.80 GRM5 (0.45) GRM5CYP2D6CA2ALDH1A1
SCHEMBL19795867 0.80 GRM5 (0.45) GRM5CYP2D6CA2ALDH1A1
SCHEMBL19803721 0.78 GRM5 (0.44) GRM5CYP2D6CA2LMNAADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7300468-A None JP disclosed
JP-H07300468-A METHOD FOR PRODUCING OPTICALLY ACTIVE 4-(2-METHYLPROPYL)-5-PHENYL-1,3-OXAZOLIDINE-2-ONE NIPPON CHEMIPHAR CO LTD 1995-11-14 JP disclosed