SCHEMBL927285

SCHEMBL927285

CCCCCCCCC=C=C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
FAAH O00519 3/20 0.43
TRPV1 Q8NER1 1/20 0.43
EP300 Q09472 1/20 0.39
THRB P10828 1/20 0.38
TERT O14746 3/20 0.38
MAPT P10636 2/20 0.38
BLM P54132 2/20 0.38
HSD17B10 Q99714 2/20 0.38
FABP4 P15090 2/20 0.38
PTPN1 P18031 2/20 0.38
PPARG P37231 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
GMNN O75496 1/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23087047 1.00 TSHR (0.48) TSHRFAAHTRPV1EP300THRB
SCHEMBL2440539 0.98
SCHEMBL4542428 0.90
SCHEMBL4421734 0.82 TSHR (0.46) TSHRFAAHTRPV1EP300THRB
SCHEMBL11811524 0.81
SCHEMBL93548 0.80 TSHR (0.52) TSHRFAAHTRPV1EP300THRB
SCHEMBL93395 0.80 TSHR (0.52) TSHRFAAHTRPV1EP300THRB
SCHEMBL548516 0.80 TSHR (0.52) TSHRFAAHTRPV1EP300THRB
SCHEMBL7776600 0.80 TSHR (0.52) TSHRFAAHTRPV1EP300THRB
SCHEMBL39394 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1037595-A4 SUNSCREEN CONCENTRATE ISP INVESTMENTS INC (US) 2001-02-14 EP claimed
CN-1279602-A Sunscreen concentrates ISP INVESTMENTS INC (US) 2001-01-10 CN claimed
EP-1037595-A1 SUNSCREEN CONCENTRATE ISP INVESTMENTS INC. (US) 2000-09-27 EP claimed
US-5916544-A TITANIUM DIOXIDE OR ZINC OXIDE WITH SUNSCREEN AND DISPERSANTS ISP INVESTMENTS INC. (US) 1999-06-29 US claimed
WO-1999024007-A1 SUNSCREEN CONCENTRATE ISP INVESTMENTS INC. (US) 1999-05-20 WO claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN disclosed
US-20220212946-A1 CERIUM (III) CARBONATE FORMULATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-07-07 US disclosed
US-20220125705-A1 TOPICAL COMPOSITIONS FOR THERMAL PROTECTION AND METHODS OF MAKING THE SAME LEARDI ENTPR LLC (US) 2022-04-28 US disclosed
EP-3937950-A1 TOPICAL COMPOSITIONS FOR THERMAL PROTECTION AND METHODS OF MAKING THE SAME Leardi Enterprises, LLC (US) 2022-01-19 EP disclosed
CN-113924077-A Cerium (III) carbonate formulations 加利福尼亚大学董事会 2022-01-11 CN disclosed
WO-2020219674-A1 CERIUM (III) CARBONATE FORMULATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-10-29 WO disclosed
WO-2020185728-A1 TOPICAL COMPOSITIONS FOR THERMAL PROTECTION AND METHODS OF MAKING THE SAME LEARDI ENTERPRISES, LLC (US) 2020-09-17 WO disclosed
WO-2001070271-A2 ACID-STABLE BASE COMPOSITIONS FOR PREPARING SURFACTANT FREE TOPICAL COMPOSITIONS COLLABORATIVE TECHNOLOGIES, INC. (US) 2001-09-27 WO disclosed
WO-2001070197-A2 METHOD FOR PREPARING HIGH PRESSURE/HIGH SHEAR DISPERSIONS CONTAINING PHYSIOLOGICALLY ACTIVE INGREDIENTS COLLABORATIVE TECHNOLOGIES, INC. (US) 2001-09-27 WO disclosed
WO-2001058238-A2 METHOD AND SYSTEM FOR PRODUCING CUSTOMIZED COSMETIC AND PHARMACEUTICAL FORMULATIONS ON DEMAND COLLABORATIVE TECHNOLOGIES, INC. (US) 2001-08-16 WO disclosed
WO-2001054663-A2 SURFACTANT FREE TOPICAL COMPOSITIONS AND METHOD FOR RAPID PREPARATION THEREOF COLLABORATIVE TECHNOLOGIES, INC. (US) 2001-08-02 WO disclosed
WO-2000068176-A1 FATTY ACID ESTERS OF AROMATIC ALCOHOLS AND THEIR USE IN COSMETIC FORMULATIONS ALZO, INC. (US) 2000-11-16 WO disclosed
EP-1006984-A1 MONOHYDRIC ALCOHOL DERIVED URETHANES AND THEIR USE IN COSMETIC FORMULATIONS Alzo, Inc. (US) 2000-06-14 EP disclosed
US-5972324-A DIMERIC URETHANE COMPOUNDS DERIVED FROM MONOHYDRIC ALCOHOLS, GENERALLY FATTY ALCOHOLS, AND A DIISOCYANATE. ALZO, INCO. (US) 1999-10-26 US disclosed
WO-1998032415-A1 MONOHYDRIC ALCOHOL DERIVED URETHANES AND THEIR USE IN COSMETIC FORMULATIONS ALZO, INC. (US) 1998-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220125705-A1 TOPICAL COMPOSITIONS FOR THERMAL PROTECTION AND METHODS OF MAKING THE SAME ANXA3, MLEC, PHOSPHO1 TSHR 4489/4885FAAH 1929/4885TRPV1 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.