Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273093 | 0.85 | AVPR1A (0.57) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9269848 | 0.85 | AVPR1A (0.60) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9275801 | 0.85 | MEN1 (0.59) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9270277 | 0.84 | KMT2A (0.59) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9275447 | 0.84 | MAPT (0.59) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9277326 | 0.84 | MAPT (0.59) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9273084 | 0.83 | PTGER1 (0.55) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9272921 | 0.82 | PTGER1 (0.57) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9272643 | 0.82 | PTGER1 (0.57) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL9275901 | 0.82 | MEN1 (0.56) | MEN1KMT2AMAPTCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461047-A | Analgesics and treats prostaglandin-E2 mediated diseases in animals | G. D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0365155-B1 | N-sulfenylated and N-acylated pyrazolines | DU PONT (US) | 1995-05-10 | — | — | EP | disclosed |
| US-5354747-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | disclosed |