Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273661 | 1.00 | MAOB (0.45) | MAOBGSK3BBACE1GRM5SMN1; SMN2 | |
| SCHEMBL9275512 | 0.91 | MAOB (0.45) | MAOBGRM5SMN1; SMN2MEN1NPC1 | |
| SCHEMBL9275513 | 0.91 | MAOB (0.45) | MAOBGRM5SMN1; SMN2MEN1NPC1 | |
| SCHEMBL9217059 | 0.87 | MAOB (0.60) | MAOBNPC1RAB9AMAOAALDH1A1 | |
| SCHEMBL9217058 | 0.87 | MAOB (0.60) | MAOBNPC1RAB9AMAOAALDH1A1 | |
| SCHEMBL9278780 | 0.84 | MAOB (0.58) | MAOBGRM5SMN1; SMN2MEN1NPC1 | |
| SCHEMBL9278781 | 0.84 | MAOB (0.58) | MAOBGRM5SMN1; SMN2MEN1NPC1 | |
| SCHEMBL9215577 | 0.82 | MAOB (0.60) | MAOBGSK3BBACE1GRM5SMN1; SMN2 | |
| SCHEMBL8877247 | 0.81 | MAOB (0.44) | MAOBGRM5SMN1; SMN2MEN1NPC1 | |
| SCHEMBL8877242 | 0.81 | MAOB (0.44) | MAOBGRM5SMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002402-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |