Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273953 | 0.92 | EPHX2 (0.60) | EPHX2EPHX1KMT2AMEN1TDP1 | |
| SCHEMBL9267546 | 0.92 | EPHX2 (0.60) | EPHX2EPHX1KMT2AMEN1TDP1 | |
| SCHEMBL9273652 | 0.92 | EPHX2 (0.60) | EPHX2EPHX1KMT2AMEN1TDP1 | |
| SCHEMBL9265695 | 0.80 | EPHX2 (0.49) | EPHX2EPHX1KMT2AMEN1TDP1 | |
| SCHEMBL9271224 | 0.80 | EPHX2 (0.49) | EPHX2EPHX1KMT2AMEN1TDP1 | |
| SCHEMBL9273423 | 0.78 | EPHX2 (0.61) | EPHX2EPHX1KMT2AMEN1TDP1 | |
| SCHEMBL9265827 | 0.77 | TRPV1 (0.53) | EPHX2TRPV1 | |
| SCHEMBL9271744 | 0.77 | EPHX2 (0.60) | EPHX2EPHX1KMT2AMEN1TDP1 | |
| SCHEMBL9269179 | 0.77 | EPHX2 (0.60) | EPHX2EPHX1KMT2AMEN1TDP1 | |
| SCHEMBL9269185 | 0.77 | EPHX2 (0.60) | EPHX2EPHX1KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |