Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275638 | 1.00 | CYP2C19 (0.34) | CYP2C19 | |
| SCHEMBL9288157 | 0.89 | FFAR3 (0.31) | — | |
| SCHEMBL648973 | 0.79 | CYP2C19 (0.38) | CYP2C19 | |
| SCHEMBL9274412 | 0.79 | FFAR3 (0.34) | — | |
| SCHEMBL9274405 | 0.79 | FFAR3 (0.34) | — | |
| SCHEMBL471835 | 0.77 | CYP2C19 (0.34) | CYP2C19 | |
| SCHEMBL9392709 | 0.76 | ATM (0.40) | — | |
| SCHEMBL9392710 | 0.76 | ATM (0.40) | — | |
| SCHEMBL9274215 | 0.75 | — | — | |
| SCHEMBL9217052 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681582-A1 | PYRAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994017069-A1 | PYRAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1994-08-04 | — | — | WO | disclosed |