Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871751 | 0.85 | KDM4E (0.55) | KDM4EHMGB1CXCL12GABRPGABRD | |
| SCHEMBL31423245 | 0.83 | KDM4E (0.53) | KDM4EHMGB1CXCL12GABRPGABRD | |
| SCHEMBL27565198 | 0.83 | KDM4E (0.53) | KDM4EHMGB1CXCL12GABRPGABRD | |
| SCHEMBL15201876 | 0.82 | HMGB1 (0.44) | KDM4EHMGB1CXCL12ALDH1A1HPGD | |
| Acetic Acid SCHEMBL28329525 | 0.81 | KDM4E (0.52) | KDM4EHMGB1CXCL12GABRPGABRD | |
| SCHEMBL27441043 | 0.81 | KDM4E (0.55) | KDM4EHMGB1CXCL12GABRPGABRD | |
| SCHEMBL9273928 | 0.81 | AKR1C4 (0.47) | KDM4EALDH1A1HPGDHSD17B10AKR1C4 | |
| SCHEMBL28051617 | 0.81 | KDM4E (0.60) | KDM4EHMGB1CXCL12GABRPGABRD | |
| SCHEMBL9273218 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL23951045 | 0.80 | KDM4E (0.50) | KDM4EHMGB1CXCL12GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643686-A1 | NEW COMPOUNDS | Astra Aktiebolag (SE) | 1995-03-22 | — | — | EP | claimed |
| WO-1993005012-A1 | NEW COMPOUNDS | AB ASTRA (SE) | 1993-03-18 | — | — | WO | claimed |
| EP-0530166-A2 | 3-Hydroxy anthranilic acid derivatives for inhibiting 3-hydroxy anthranilate oxygenase | Astra Aktiebolag (SE) | 1993-03-03 | — | — | EP | claimed |
| EP-0643686-A1 | NEW COMPOUNDS | Astra Aktiebolag (SE) | 1995-03-22 | — | — | EP | disclosed |
| WO-1993005012-A1 | NEW COMPOUNDS | AB ASTRA (SE) | 1993-03-18 | — | — | WO | disclosed |
| EP-0530166-A2 | 3-Hydroxy anthranilic acid derivatives for inhibiting 3-hydroxy anthranilate oxygenase | Astra Aktiebolag (SE) | 1993-03-03 | — | — | EP | disclosed |