Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.64 |
| ▸ | IDH1 | O75874 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9276395 | 1.00 | PTPN1 (0.64) | PTPN1IDH1ABCB1UGT1A1DPP4 | |
| SCHEMBL9273302 | 0.92 | PTPN1 (0.54) | PTPN1 | |
| SCHEMBL9273307 | 0.92 | PTPN1 (0.54) | PTPN1 | |
| SCHEMBL7186479 | 0.91 | DPP4 (0.57) | PTPN1IDH1ABCB1UGT1A1DPP4 | |
| SCHEMBL7191554 | 0.91 | PTPN1 (0.77) | PTPN1 | |
| SCHEMBL7186473 | 0.91 | DPP4 (0.57) | PTPN1IDH1ABCB1UGT1A1DPP4 | |
| SCHEMBL7191546 | 0.91 | PTPN1 (0.77) | PTPN1 | |
| SCHEMBL9279126 | 0.88 | PTPN1 (0.64) | PTPN1IDH1ABCB1UGT1A1DPP4 | |
| SCHEMBL9279124 | 0.88 | PTPN1 (0.64) | PTPN1IDH1ABCB1UGT1A1DPP4 | |
| SCHEMBL7190248 | 0.84 | PTPN1 (0.65) | PTPN1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |