Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.61 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | CPS1 | P31327 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856415 | 0.86 | PARP10 (0.64) | PARP10PARP15SCN9AFFAR4PARP2 | |
| SCHEMBL13366219 | 0.84 | KDM4E (0.50) | CPS1CA12CA1CA2CA7 | |
| SCHEMBL927683 | 0.82 | PARP10 (0.68) | PARP10PARP15SCN9AFFAR4PARP2 | |
| SCHEMBL8014781 | 0.82 | PARP10 (0.55) | PARP10PARP15SCN9AFFAR4PARP2 | |
| SCHEMBL8014783 | 0.82 | PARP10 (0.55) | PARP10PARP15SCN9AFFAR4PARP2 | |
| SCHEMBL8020684 | 0.80 | PARP10 (0.53) | PARP10PARP15SCN9AFFAR4PARP2 | |
| SCHEMBL8020689 | 0.80 | PARP10 (0.53) | PARP10PARP15SCN9AFFAR4PARP2 | |
| SCHEMBL8005480 | 0.79 | PARP10 (0.55) | PARP10PARP15SCN9AFFAR4PARP2 | |
| SCHEMBL8005475 | 0.79 | PARP10 (0.55) | PARP10PARP15SCN9AFFAR4PARP2 | |
| SCHEMBL8021405 | 0.79 | PARP10 (0.52) | PARP10PARP15SCN9AFFAR4PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015225-A1 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-01-20 | — | — | US | disclosed |
| US-20110015225-A1 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-01-20 | — | — | US | disclosed |
| US-20110015225-A1 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-01-20 | — | — | US | disclosed |
| EP-2261213-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-12-15 | — | — | EP | disclosed |
| EP-2261213-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015225-A1 | Heterocyclic compound | MC1R, MCHR1, MCHR2 | PARP10 4541/4885PARP15 4553/4885SCN9A 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.