Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914067 | 0.70 | — | — | |
| SCHEMBL4912130 | 0.64 | — | — | |
| Naphthalene SCHEMBL10892164 | 0.64 | CYP2A6 (0.47) | CYP1A2ALDH1A1CYP2A6ALOX12TLR8 | |
| SCHEMBL23860138 | 0.63 | CYP1A2 (0.40) | CYP1A2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL129937 | 0.62 | CYP2A6 (0.44) | ALDH1A1CYP2A6ALOX12MAPTKDM4E | |
| Naphthalene SCHEMBL28460931 | 0.58 | CYP2A6 (0.57) | CYP1A2ALDH1A1CYP2A6ALOX12UGT2B7 | |
| Naphthalene SCHEMBL28234791 | 0.58 | CYP2A6 (0.57) | ALDH1A1CYP2A6ALOX12UGT2B7KDM4E | |
| Naphthalene SCHEMBL8038891 | 0.58 | CYP2A6 (0.57) | CYP1A2ALDH1A1CYP2A6ALOX12UGT2B7 | |
| Naphthalene SCHEMBL10612593 | 0.58 | CYP2A6 (0.57) | CYP1A2ALDH1A1CYP2A6ALOX12MAPT | |
| Naphthalene SCHEMBL329435 | 0.58 | CYP2A6 (0.89) | CYP1A2ALDH1A1CYP2A6ALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855438-A2 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES | Galleon Pharmaceuticals, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013181217-A2 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES | GALLEON PHARMACEUTICALS, INC. (US) | 2013-12-05 | — | — | WO | disclosed |
| EP-2646423-A1 | NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES | Galleon Pharmaceuticals, Inc. (US) | 2013-10-09 | — | — | EP | disclosed |
| WO-2012074999-A1 | NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES | GALLEON PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | WO | disclosed |