Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278676 | 1.00 | POLB (0.33) | POLBPKMEPHX2 | |
| SCHEMBL8608407 | 1.00 | POLB (0.33) | POLBPKMEPHX2 | |
| SCHEMBL9791763 | 1.00 | POLB (0.33) | POLBPKMEPHX2 | |
| SCHEMBL27877190 | 0.89 | POLB (0.39) | POLBPKMEPHX2 | |
| SCHEMBL27877191 | 0.89 | POLB (0.39) | POLBPKMEPHX2 | |
| SCHEMBL11793061 | 0.79 | — | — | |
| SCHEMBL8610183 | 0.77 | BTK (0.52) | EPHX2 | |
| SCHEMBL9990454 | 0.77 | BTK (0.52) | EPHX2 | |
| SCHEMBL17220409 | 0.77 | BTK (0.52) | EPHX2 | |
| SCHEMBL17260538 | 0.77 | BTK (0.52) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680488-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017090-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |